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KMID : 0354720060300060435
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Journal of Korean Diabetes Association
2006 Volume.30 No. 6 p.435 ~ p.441
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Effects of Type 2 Diabetes Mellitus on Risk Factors of Acute Coronary Syndrome
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Moon Hong-Ju
Cho Min-Ho
Kang Jun-Goo
Lee Byung-Wan
Park Cheol-Young
Lee Seong-Jin
Hong Eun-Gyoung
Yoo Jae-Myung
Kim Doo-Man
Ihm Sung-Hee
Kim Hyeon-Kyu
Rim Chong-Yun
Choi Moon-Gi
Yoo Hyung-Joon
Park Sung-Woo
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Abstract
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Background:Diabetes mellitus (DM) is equivalent as well a risk factor of cardiovascular disease. We analyzed the effects of DM on clinical risk factors of acute coronary syndrome by comparing DM group with Non-DM group.
Methods:A total of 847 (514 males and 333 females) patients with acute coronary syndrome was selected from 1664 patients who had undergone coronary angiography (CAG). These patients comprised 105 subjects with non-ST elevation myocardial infarction (MI), 313 with ST elevation MI and 429 with unstable angina. According to the presence
of DM, we retrospectively reviewed the measured basic demographics, biochemical
markers and coronary angiographic findings.
Results:In the multivariated analysis, history of hypertension (P = 0.001), C-reactive protein (CRP) level (P = 0.001) and triglyceride level (P = 0.018) were independent risk factors in type 2 diabetic group. Also the frequency of multiple coronary vessel disease was higher in DM group than non-DM group on the coronary angiographic finding
Conclusions: Classic risk factors for acute coronary syndrome are strong predictors in patients with type 2 DM. Among these factors, the most important powerful risk factor is history of hypertension
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KEYWORD
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Acute coronary syndrome, Diabetes mellitus, Risk factors
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